Ironically, Fantagraphics is probably thriving right now because they are publishing Peanuts which, while it has more than its share of angst, is about as popular and mainstream as comics get.
PEANUTS saved Fantagraphics, yeah. Given that they were on the verge of bankruptcy before it, due to distributor defaults, the question of whether it puts them into "thriving" territory is an open one.
Certainly, nobody there is getting rich.
kdb